Some of my favorite adult anime:
Nana
Monster
Stepped Up Love Story
Elfin Lied
Perfect Blue
Miss Hokusai
Black Lagoon
Nana is about two 20-something girls both named Nana, who meet by chance on a train and end up being roommates. After that, life happens -- though not always for the best. Their friendship grows, but then becomes strained. The series gives us two good character studies, with a strong cast of supporting characters. Nana is not just a slice of life anime, but slices of life.
I'll talk about the others later.
Bookmarks